Research

Current opinions on the present and future use of functional near-infrared spectroscopy (fNIRS) in psychiatry

Prof. Allan Reiss, Prof. Manish Saggar, Prof. Hadi Hosseini et al discuss many applications of fNIRS in psychiatry, protype wearable fNIRS devices, and future integration of EEG, eye tracking, heart rate and artificial intelligence to enable effective personalized monitoring, diagnosis, and treatment for patients with psychiatric disorders.

Neuromorphic sensorimotor loop embodied by monolithically integrated, low-voltage, soft e-skin

Prof. Zhenan Bao et al report an electronic skin that incorporates organic semiconductor transistors and has no rigid components, thus mimicking aspects of real skin in mechanical properties, sensing temperature and pressure and can encode these stimuli into electrical pulses.

Decoupling transmission and transduction for improved durability of highly stretchable, soft strain sensing: Applications in human health monitoring

Prof. Mark Cutkosky, Prof. Doff McElhinney et al present a modular approach that includes a soft, elastomeric microelectromechanical system (MEMS) optimized for application-specific performance and demonstrate an implantable cardiac sensor for measuring global longitudinal strain.

Characterization of a 30 µm pixel size CLIP-based 3D printer and its enhancement through dynamic printing optimization

Prof. Joseph DeSimone et al demonstrate a micro-CLIP 3D printing capability to manufacture finely detailed and gradient 3D structures, such as terraced microneedle arrays and micro-lattice structures, while maintaining high print speeds.

Multi-omics microsampling for the profiling of lifestyle-associated changes in health

Prof. Michael Snyder et al describe a strategy for the frequent collection and analysis of thousands of metabolites, lipids, cytokines and proteins in 10 μl of blood alongside physiological information from wearable sensors and demonstrate its advantages for discovering individualized inflammatory and metabolic responses to complex dietary changes and for deep individualized profiling.

A substrate-less nanomesh receptor with meta-learning for rapid hand task recognition

Prof. Zhenan Bao et al present a novel, electrically active, spray-on smart skin that uses AI to rapidly decipher typing, sign language, and the shape of a familiar object from the movements of a human hand even with limited training.

Wireless closed-loop smart bandage for chronic wound management and accelerated tissue regeneration

Prof. Zhenan Bao, Prof. Geoffrey Gurtner et al have developed a prototype wireless smart bandage that speeds tissue repair, promotes faster closure of wounds, increases new blood flow to injured tissue, and enhances the recovery of skin.

Characterization and modeling of partial-thickness cutaneous injury from debris-simulating kinetic projectiles

Prof. Reinhold Dauskardt et al develop predictive models of injuries to skin due to projectiles, using simulation of projectile size, shape, orientation, friction coefficient, and impact angle.

Hexagonal ring origami assemblies: Foldable functional structures with extreme packing

Prof. Renee Zhao et al report a design strategy for snap-folding hexagonal rings that can be folded to 1.5% and 0.4% of initial area and volume, respectively, for future applications as stints, novel medical devices, and soft robotics.

A flexible electronic strain sensor for the real-time monitoring of tumor regression

Prof. Zhenan Bao, Prof. Parag Mallick, Prof. William Hiesinger et al develop and demonstrate a proof-of-concept wireless device that that adheres to the skin to measure changes in tumor size below.